Time Zone – GMT-4 (America/New_York)
| 1 | MLS All-Stars | Liga MX All-Stars |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Vancouver Whitecaps | 17 | 10 | 5 | 2 | 31:14 | 17 | 35 |
| 2 | San Diego FC | 18 | 10 | 3 | 5 | 33:20 | 13 | 33 |
| 3 | Minnesota United | 18 | 8 | 6 | 4 | 28:20 | 8 | 30 |
| 4 | Portland Timbers | 18 | 8 | 6 | 4 | 28:24 | 4 | 30 |
| 5 | Los Angeles FC | 16 | 7 | 5 | 4 | 30:23 | 7 | 26 |
| 6 | Seattle Sounders | 18 | 7 | 5 | 6 | 25:25 | 0 | 26 |
| 7 | Austin FC | 19 | 7 | 5 | 7 | 15:21 | -6 | 26 |
| 8 | San Jose Earthquakes | 18 | 6 | 5 | 7 | 35:29 | 6 | 23 |
| 9 | Colorado Rapids | 18 | 6 | 4 | 8 | 18:25 | -7 | 22 |
| 10 | FC Dallas | 17 | 5 | 6 | 6 | 22:28 | -6 | 21 |
| 11 | Houston Dynamo | 18 | 5 | 5 | 8 | 23:28 | -5 | 20 |
| 12 | Real Salt Lake | 18 | 5 | 3 | 10 | 18:25 | -7 | 18 |
| 13 | Sporting Kansas City | 18 | 4 | 4 | 10 | 28:35 | -7 | 16 |
| 14 | St. Louis City | 18 | 3 | 6 | 9 | 17:26 | -9 | 15 |
| 15 | Los Angeles Galaxy | 18 | 1 | 5 | 12 | 18:39 | -21 | 8 |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Philadelphia Union | 18 | 11 | 4 | 3 | 34:19 | 15 | 37 |
| 2 | FC Cincinnati | 18 | 10 | 3 | 5 | 26:24 | 2 | 33 |
| 3 | Nashville SC | 18 | 9 | 5 | 4 | 32:21 | 11 | 32 |
| 4 | Columbus Crew | 18 | 8 | 7 | 3 | 29:25 | 4 | 31 |
| 5 | Orlando City | 18 | 8 | 6 | 4 | 32:22 | 10 | 30 |
| 6 | Inter Miami | 16 | 8 | 5 | 3 | 36:27 | 9 | 29 |
| 7 | New York City | 18 | 8 | 4 | 6 | 24:20 | 4 | 28 |
| 8 | New York Red Bulls | 18 | 8 | 3 | 7 | 29:21 | 8 | 27 |
| 9 | Charlotte | 18 | 8 | 1 | 9 | 29:29 | 0 | 25 |
| 10 | Chicago Fire | 17 | 7 | 4 | 6 | 35:31 | 4 | 25 |
| 11 | New England Revolution | 16 | 6 | 5 | 5 | 19:15 | 4 | 23 |
| 12 | DC United | 19 | 4 | 6 | 9 | 17:38 | -21 | 18 |
| 13 | Atlanta Utd | 18 | 4 | 5 | 9 | 21:34 | -13 | 17 |
| 14 | Toronto FC | 17 | 3 | 4 | 10 | 18:24 | -6 | 13 |
| 15 | CF Montreal | 18 | 2 | 5 | 11 | 15:33 | -18 | 11 |
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