Time Zone – GMT-5 (America/New_York)
| 1 | Feyenoord | Bye | |
| 5 | Utrecht | Bye | |
| 8 | Bye | Waalwijk | |
| 9 | PSV | Bye | |
| 16 | Bye | Twente | |
| 17 | Hardenberg | Bye | |
| 20 | Bye | Heracles | |
| 24 | Bye | AZ Alkmaar | |
| 25 | ADO 20 Heemskerk | Bye | |
| 26 | Bye | Quick Boys | |
| 28 | Bye | NAC Breda | |
| 29 | De Graafschap | Bye | |
| 32 | Bye | FC Emmen | |
| 33 | Spakenburg | Bye | |
| 34 | RKVV Zwaluw | VV Scherpenzeel | 1 : 5 |
| 36 | Bye | Helmond | |
| 37 | Den Bosch | Bye | |
| 40 | Bye | Excelsior | |
| 41 | SJC Noordwijk | Bon Boys | 2 : 1 |
| 42 | Kampong | Gemert | 2 : 4 |
| 44 | Bye | Willem II | |
| 45 | Rijnsburgse Boys | Bye | |
| 48 | Bye | Groningen | |
| 49 | Katwijk | Bye | |
| 51 | TEC | VV DOVO | 2 : 1 |
| 52 | Avanti | Meerssen | 0 : 3 |
| 53 | CSV Apeldoorn | ODIN '59 | 1 : 0 |
| 54 | Rosmalen | OSS '20 | 5 : 1 |
| 56 | Bye | Almere City | |
| 57 | Oss | Bye | |
| 60 | Bye | Eindhoven FC | |
| 61 | Sparta Nijkerk | ONS Sneek | 2 : 0 |
| 62 | GVV Unitas | Blauw Wit | 4 : 0 |
| 64 | Bye | Sittard | |
| 65 | Scheveningen | Bye | |
| 66 | Hoek | SteDoCo | 3 : 2 |
| 67 | ACV Assen | Bye | |
| 68 | USV Hercules | VV Berkum | 2 : 1 |
| 72 | Bye | Ajax | |
| 73 | Lisse | Bye | |
| 74 | Blauw Geel | SVOD | 5 : 1 |
| 76 | Bye | Dordrecht | |
| 77 | Cambuur | Bye | |
| 80 | Bye | Maastricht | |
| 81 | Groene Ster | Groen Wit | 6 : 0 |
| 82 | Bye | Kozakken Boys | |
| 84 | Bye | Vitesse | |
| 85 | Heerenveen | Bye | |
| 88 | Bye | Venlo | |
| 89 | Nieuwkoop | RKAV Volendam | 0 : 2 |
| 90 | Westlandia | HV & CV Quick | 3 : 1 |
| 91 | Eemdijk | Bunde | 5 : 0 |
| 92 | HSC '21 | Harkemase Boys | 3 : 4 |
| 93 | AFC | Bye | |
| 96 | Bye | Zwolle | |
| 97 | GVVV | Bye | |
| 98 | Barendrecht | Genemuiden | 2 : 1 |
| 100 | Bye | Telstar | |
| 101 | Nijmegen | Bye | |
| 104 | Bye | Roda | |
| 105 | Kloetinge | BOL | 6 : 0 |
| 106 | Bye | HFC | |
| 108 | Bye | G.A. Eagles | |
| 109 | Veensche Boys | Heesch | 1 : 2 |
| 110 | Bye | De Treffers | |
| 111 | VVSB | Rijnvogels | 4 : 3 |
| 112 | Jubbega | UNA | 3 : 5 |
| 113 | DEM | Xerxes DZB | 1 : 0 |
| 114 | Purmersteijn | Sportlust | 0 : 2 |
| 115 | Baronie | Hoogeveen | 0 : 1 |
| 116 | AWC | Staphorst | 1 : 2 |
| 117 | Nuenen | VV Chevremont | 4 : 2 |
| 118 | Bye | Excelsior Maassluis | |
| 120 | Bye | FC Volendam | |
| 121 | AGB | Olde Veste | 1 : 2 |
| 122 | Bye | Noordwijk | |
| 124 | Bye | Den Haag | |
| 125 | DVS '33 Ermelo | Urk | 1 : 0 |
| 126 | IJsselmeervogels | TOGB | 2 : 1 |
| 128 | Bye | Sparta Rotterdam |
| 1 | Feyenoord | Bye | |
| 3 | Utrecht | Bye | |
| 4 | Bye | Waalwijk | |
| 5 | PSV | Bye | |
| 8 | Bye | Twente | |
| 9 | Hardenberg | Bye | |
| 10 | Bye | Heracles | |
| 12 | Bye | AZ Alkmaar | |
| 13 | ADO 20 Heemskerk | Quick Boys | 0 : 1 |
| 14 | Bye | NAC Breda | |
| 15 | De Graafschap | Bye | |
| 16 | Bye | FC Emmen | |
| 17 | Spakenburg | VV Scherpenzeel | 1 : 0 |
| 18 | Bye | Helmond | |
| 19 | Den Bosch | Bye | |
| 20 | Bye | Excelsior | |
| 21 | SJC Noordwijk | Gemert | 1 : 0 |
| 22 | Bye | Willem II | |
| 23 | Rijnsburgse Boys | Bye | |
| 24 | Bye | Groningen | |
| 25 | Katwijk | Bye | |
| 26 | TEC | Meerssen | 2 : 0 |
| 27 | CSV Apeldoorn | Rosmalen | 1 : 3 |
| 28 | Bye | Almere City | |
| 29 | Oss | Bye | |
| 30 | Bye | Eindhoven FC | |
| 31 | Sparta Nijkerk | GVV Unitas | 4 : 2 |
| 32 | Bye | Sittard | |
| 33 | Scheveningen | Hoek | 2 : 1 |
| 34 | ACV Assen | USV Hercules | 1 : 5 |
| 36 | Bye | Ajax | |
| 37 | Lisse | Blauw Geel | 1 : 0 |
| 38 | Bye | Dordrecht | |
| 39 | Cambuur | Bye | |
| 40 | Bye | Maastricht | |
| 41 | Groene Ster | Kozakken Boys | 1 : 0 |
| 42 | Bye | Vitesse | |
| 43 | Heerenveen | Bye | |
| 44 | Bye | Venlo | |
| 45 | RKAV Volendam | Westlandia | 3 : 0 |
| 46 | Eemdijk | Harkemase Boys | 3 : 2 |
| 47 | AFC | Bye | |
| 48 | Bye | Zwolle | |
| 49 | GVVV | Barendrecht | 5 : 2 |
| 50 | Bye | Telstar | |
| 51 | Nijmegen | Bye | |
| 52 | Bye | Roda | |
| 53 | Kloetinge | HFC | 1 : 3 |
| 54 | Bye | G.A. Eagles | |
| 55 | Heesch | De Treffers | 1 : 3 |
| 56 | VVSB | UNA | 1 : 2 |
| 57 | DEM | Sportlust | 3 : 1 |
| 58 | Hoogeveen | Staphorst | 3 : 0 |
| 59 | Nuenen | Excelsior Maassluis | 0 : 1 |
| 60 | Bye | FC Volendam | |
| 61 | Olde Veste | Noordwijk | 0 : 2 |
| 62 | Bye | Den Haag | |
| 63 | DVS '33 Ermelo | IJsselmeervogels | 0 : 2 |
| 64 | Bye | Sparta Rotterdam |
| 1 | Feyenoord | Bye | |
| 2 | Utrecht | Waalwijk | 3 : 2 |
| 3 | PSV | Bye | |
| 4 | Bye | Twente | |
| 5 | Hardenberg | Heracles | 2 : 0 |
| 6 | Bye | AZ Alkmaar | |
| 7 | Quick Boys | NAC Breda | 1 : 0 |
| 8 | De Graafschap | FC Emmen | 2 : 0 |
| 9 | Spakenburg | Helmond | 3 : 1 |
| 10 | Den Bosch | Excelsior | 1 : 2 |
| 11 | SJC Noordwijk | Willem II | 1 : 3 |
| 12 | Rijnsburgse Boys | Groningen | 0 : 1 |
| 13 | Katwijk | TEC | 5 : 0 |
| 14 | Rosmalen | Almere City | 1 : 8 |
| 15 | Oss | Eindhoven FC | 0 : 1 |
| 16 | Sparta Nijkerk | Sittard | 0 : 1 |
| 17 | Scheveningen | USV Hercules | 0 : 1 |
| 18 | Bye | Ajax | |
| 19 | Lisse | Dordrecht | 1 : 3 |
| 20 | Cambuur | Maastricht | 4 : 1 |
| 21 | Groene Ster | Vitesse | 0 : 1 |
| 22 | Heerenveen | Venlo | 5 : 1 |
| 23 | RKAV Volendam | Eemdijk | 5 : 0 |
| 24 | AFC | Zwolle | 1 : 0 |
| 25 | GVVV | Telstar | 1 : 0 |
| 26 | Nijmegen | Roda | 5 : 3 |
| 27 | HFC | G.A. Eagles | 1 : 4 |
| 28 | De Treffers | UNA | 4 : 0 |
| 29 | DEM | Hoogeveen | 3 : 1 |
| 30 | Excelsior Maassluis | FC Volendam | 1 : 0 |
| 31 | Noordwijk | Den Haag | 0 : 1 |
| 32 | IJsselmeervogels | Sparta Rotterdam | 0 : 2 |
| 1 | Feyenoord | Utrecht | 2 : 1 |
| 2 | PSV | Twente | 3 : 1 |
| 3 | Hardenberg | AZ Alkmaar | 2 : 3 |
| 4 | Quick Boys | De Graafschap | 2 : 0 |
| 5 | Spakenburg | Excelsior | 2 : 3 |
| 6 | Willem II | Groningen | 1 : 3 |
| 7 | Katwijk | Almere City | 1 : 2 |
| 8 | Eindhoven FC | Sittard | 0 : 2 |
| 9 | USV Hercules | Ajax | 3 : 2 |
| 10 | Dordrecht | Cambuur | 0 : 3 |
| 11 | Vitesse | Heerenveen | 1 : 0 |
| 12 | RKAV Volendam | AFC | 0 : 1 |
| 13 | GVVV | Nijmegen | 1 : 6 |
| 14 | G.A. Eagles | De Treffers | 7 : 1 |
| 15 | DEM | Excelsior Maassluis | 0 : 1 |
| 16 | Den Haag | Sparta Rotterdam | 2 : 0 |
| 1 | Feyenoord | PSV | 1 : 0 |
| 2 | AZ Alkmaar | Quick Boys | 4 : 3 |
| 3 | Excelsior | Groningen | 0 : 2 |
| 4 | Almere City | Sittard | 1 : 2 |
| 5 | USV Hercules | Cambuur | 3 : 4 |
| 6 | Vitesse | AFC | 1 : 0 |
| 7 | Nijmegen | G.A. Eagles | 2 : 1 |
| 8 | Excelsior Maassluis | Den Haag | 1 : 2 |
| 1 | Feyenoord | AZ Alkmaar | 2 : 0 |
| 2 | Groningen | Sittard | 1 : 0 |
| 3 | Cambuur | Vitesse | 3 : 1 |
| 4 | Nijmegen | Den Haag | 3 : 0 |
| 1 | Feyenoord | Groningen | 2 : 1 |
| 2 | Cambuur | Nijmegen | 1 : 2 |
| 1 | Feyenoord | Nijmegen | 1 : 0 |
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